Nucleation landscape of biomolecular condensates – Nature

  • 1.

    Shin, Y. & Brangwynne, C. P. Liquid section condensation in cell physiology and illness. Science 357, eaar4382 (2017).

    Article  Google Scholar 

  • 2.

    Banani, S. F., Lee, H. O., Hyman, A. A. & Rosen, M. Ok. Biomolecular condensates: organizers of mobile biochemistry. Nat. Rev. Mol. Cell Biol. 18, 285–298 (2017).

    CAS  Article  Google Scholar 

  • 3.

    Kashchiev, D. Nucleation (Elsevier, 2000).

  • 4.

    Auer, S. & Frenkel, D. Prediction of absolute crystal-nucleation fee in arduous-sphere colloids. Nature 409, 1020–1023 (2001).

    ADS  CAS  Article  Google Scholar 

  • 5.

    Mitrea, D. M. et al. Nucleophosmin integrates inside the nucleolus by way of multi-modal interactions with proteins displaying R-wealthy linear motifs and rRNA. eLife 5, e13571 (2016).

    Article  Google Scholar 

  • 6.

    Sanders, D. W. et al. Competing protein-RNA interplay networks management multiphase intracellular group. Cell 181, 306–324.e28 (2020).

    CAS  Article  Google Scholar 

  • 7.

    Martin, E. W. et al. Valence and patterning of fragrant residues decide the section conduct of prion-like domains. Science 367, 694–699 (2020).

    ADS  CAS  Article  Google Scholar 

  • 8.

    Wang, J. et al. A molecular grammar governing the driving forces for section separation of prion-like RNA binding proteins. Cell 174, 688–699.e16 (2018).

    CAS  Article  Google Scholar 

  • 9.

    Bracha, D. et al. Mapping native and world liquid section conduct in residing cells utilizing picture-oligomerizable seeds. Cell 175, 1467–1480 (2018).

    CAS  Article  Google Scholar 

  • 10.

    Shin, Y. et al. Liquid nuclear condensates mechanically sense and restructure the genome. Cell 175, 1481–1491.e13 (2018).

    CAS  Article  Google Scholar 

  • 11.

    Wei, M. T. et al. Nucleated transcriptional condensates amplify gene expression. Nat. Cell Biol. 22, 1187–1196 (2020).

    CAS  Google Scholar 

  • 12.

    Kato, M. et al. Cell-free formation of RNA granules: low complexity sequence domains type dynamic fibers inside hydrogels. Cell 149, 753–767 (2012).

    CAS  Article  Google Scholar 

  • 13.

    Riback, J. A. et al. Composition-dependent thermodynamics of intracellular section separation. Nature 581, 209–214 (2020).

    ADS  CAS  Article  Google Scholar 

  • 14.

    Rubinstein, M. & Colby, R. H. Polymer Physics (Oxford Univ. Press, 2003).

  • 15.

    Clouet, E. Modeling of Nucleation Processes (ASM Handbook, 2009).

  • 16.

    Honerkamp-Smith, A. R., Veatch, S. L. & Keller, S. L. An introduction to vital factors for biophysicists; observations of compositional heterogeneity in lipid membranes. Biochim. Biophys. Acta 1788, 53–63 (2009).

    CAS  Article  Google Scholar 

  • 17.

    Mayoral, E. & Goicochea, A. G. Hyperscaling relationship between the interfacial rigidity of liquids and their correlation size close to the vital level. Soft Matter 10, 9054–9058 (2014).

    ADS  CAS  Article  Google Scholar 

  • 18.

    Lafontaine, D. L., Riback, J. A., Bascetin, R. & Brangwynne, C. P. The nucleolus as a multiphase liquid condensate. Nat. Rev. Mol. Cell Biol. 22, 165–182 (2021).

    CAS  Article  Google Scholar 

  • 19.

    Cho, W. Ok. et al. Mediator and RNA polymerase II clusters affiliate in transcription-dependent condensates. Science 361, 412–415 (2018).

    ADS  CAS  Article  Google Scholar 

  • 20.

    Chong, S. et al. Imaging dynamic and selective low-complexity area interactions that management gene transcription. Science 361, eaar2555 (2018).

    Article  Google Scholar 

  • 21.

    Sabari, B. R. et al. Coactivator condensation at tremendous-enhancers hyperlinks section separation and gene management. Science 361, eaar3958 (2018).

    Article  Google Scholar 

  • 22.

    Kilic, S. et al. Phase separation of 53 BP1 determines liquid-like conduct of DNA restore compartments. EMBO J. 38, e101379 (2019).

    Article  Google Scholar 

  • 23.

    Shevtsov, S. P. & Dundr, M. Nucleation of nuclear our bodies by RNA. Nat. Cell Biol. 13, 167–173 (2011).

    CAS  Article  Google Scholar 

  • 24.

    Berry, J., Weber, S. C., Vaidya, N., Haataja, M. & Brangwynne, C. P. RNA transcription modulates section transition-pushed nuclear physique meeting. Proc. Natl. Acad. Sci. 112, E5237–E5245 (2015).

    ADS  CAS  Article  Google Scholar 

  • 25.

    Aaron, J. S., Taylor, A. B. & Chew, T. L. Image co-localization—co-prevalence versus correlation. J. Cell Sci. 131, jcs211847 (2018).

    Article  Google Scholar 

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